Cefixime-400 is a semi-synthetic, broad spectrum cephalosporin antibiotic of third generation for oral administration. It is a bactericidal antibiotic, kills bacteria by interfering in the synthesis of the bacterial cell wall. Cefixime-400 is highly stable in the presence of beta-lactamase enzymes. Cefixime-400 has marked in -vitro bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms including beta lactamase producers.
Clinical efficacy of Cefixime-400 has been demonstrated in infections caused by commonly occurring pathogens including Gram-positive organism Streptococcus pneumoniae, Streptococcus pyogenes, Gram-negative organism Escherichia coli, Proteus mirabilis, Klebsiella spp., Haemophilus influenzae (beta-lactamase positive and negative), Moraxella catarrhalis (beta-lactamase positive and negative), Salmonella typhi and Enterobacter species.
Cefixime-400, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime-400 is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall.
Brand name: Zobifixime-400 Tablets
Dosage forms: oral capsule, oral powder for reconstitution, oral tablet, oral chewable tablet
Drug class: Third generation cephalosporins
Manufacturer: PUIZER PHARMACEUTICAL.
Country of Origin: Made in India.
