Ampicillin trihydrate is a semisynthetic penicillin derived from the basic penicillin nucleus, 6-aminopenicillanic acid. Ampicillin is designated chemically as (2S, 5R, 6R)-6-[(R)-2-Amino-2-phenylacetamido]-3, 3-dimethyl-7-oxo-4-thia-l-azabicyclo [3.2.0] heptane-2-carboxylic acid trihydrate.
Ampicillin is bactericidal at low concentrations and is clinically effective not only against the gram-positive organisms usually susceptible to penicillin G but also against a variety of gram-negative organisms. It is stable in the presence of gastric acid and is well absorbed from the gastrointestinal tract.
Ampicillin is similar to penicillin in its bactericidal action against susceptible bacteria during the stage of active multiplication. It acts through the inhibition of cell wall biosynthesis that leads to the death of the bacteria.
Brand: ZEVCILLIN-500 Capsules (Ampicillin Capsules I.P. 500 mg)
Dosage form: Capsule.
Drug class: Aminopenicillins.
Manufacturer: PUIZER PHARMACEUTICAL (OPC).
Country of Origin: Made in India.
